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BTS guidelines for the management of community acquired pneumonia in adults: update 2009
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Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD
1 Respiratory Cell and Molecular Biology, Division of Infection, Inflammation and Repair, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK 2 Department of Molecular ...
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Lung cancer in HIV infected patients: facts, questions and challenges
AIDS related mortality has fallen sharply in industrialised countries since 1996 following the introduction of highly active antiretroviral therapy. This has been accompanied by an increase in the ...
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Lymphangioleiomyomatosis: clinical features, management and basic mechanisms
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Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD
Division of Pulmonary Disease and Laboratory of Cytoimmunopathology of Heart and Lung, Salvatore Maugeri Foundation, IRCCS, Veruno, Italy Background: Increased numbers of activated neutrophils have ...
thorax.bmj1d
Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores
Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported outcome measure assessing symptoms, functioning and health-related quality of life for patients with ...
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No demonstrable effect of S-carboxymethylcysteine on clearance of secretions from the human lung.
The mucolytic efficacy of S-carboxymethylcysteine has been assessed in a double-blind crossover trial in 16 patients with chronic obstructive bronchitis. No significant difference was found between ...
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Incidence and characteristics of viral community-acquired pneumonia in adults
Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...
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Development of the bronchial epithelial reticular basement membrane: relationship to epithelial height and age
Background The bronchial epithelium and underlying reticular basement membrane (RBM) have a close spatial and functional inter-relationship and are considered an epithelial–mesenchymal trophic unit ...
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Online First
Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators ...
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Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial
1 Department of Respiratory Medicine, Norfolk & Norwich University Hospital, Norwich, UK 2 School of Medicine Health Policy & Practice, University of East Anglia, Norwich, UK Correspondence to Dr ...
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Cost effectiveness of an outpatient multidisciplinary pulmonary rehabilitation programme
BACKGROUND Pulmonary rehabilitation programmes improve the health of patients disabled by lung disease but their cost effectiveness is unproved. We undertook a cost/utility analysis in conjunction ...